polymericmicelles相关论文
Gemcitabine (GEM) is the most potent anti-cancer drug for the treatment of pancreatic cancer.However,it undergoes rapid ......
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Folate and CPP mediated specific delivery of camptothecin to tumor via pH and reduction dual-sensiti
Camptothecin (CPT) is a naturally occurring alkaloid that shows good antitumor activity in vitro against various tumor c......
Polymeric micelles are under investigation as delivery vehicles for various anticancer drugs [1,2].However,these systems......
Targeting tumors with long-circulating polymeric micelles is a promising strategy in systemic cancer treatment.This carr......
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Π-Π stacking stabilized polymeric micelles loaded with hydrophobic photosensitizer or chemotherapeut
Polymeric micelles (PM) have been extensively investigated for tumor-targeted delivery of hydrophobic therapeutic agents......
Nanotechnology-based medicine (Nanomedicine) has received progressive interest for the treatment of intractable diseases......
Objective :To study Carboxymethyl Chitosan-Rhein conjugate(CR conjugate)effects intestinal absorption of Paclitaxel(PTX)......
Polymeric micelles(PMs)have been widely proven to enhance the oral bioavailibility of poorly water-soluble drugs.However......
Aim: To investigate the transport properties of polymeric micelles across Madin Darby Canine Kidney (MDCK) cells.Methods......
Cationic micelles based on PEG-PLL-PLLeu hybrid polypeptides as highly effective drug and gene vecto
Developing safe, effective drug and nonviral gene vectors are highly crucial for successful chemical drug therapy and ge......
Mitochondria are important targets for the intracellular delivery of drugs and DNA.For mitochondria-targeting delivery,a......
Synthesis and characterization of low-density lipoprotein modified poly-N-succinyl chitosan lipoic a
Objective: In this paper, we report on reduction and pH dual-sensitive reversibly core-crosslinked micelles based on N-s......
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Characterization and modulation of drug resistance of chemical conjugation of Methotrexate in Pluron
Multidrug resistance (MDR) in cancer is a major cause for the failure of anti-cancer chemotherapy with elevated expressi......
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Polymeric micelles are generally constructed with a protecting shell of a hydrophilic polymer for shellingthe hydrophobi......
Multi-scale simulations of pH-sensitive self-assembled micelles for controlled anticancer drug DOX r
Doxorubicin(DOX)is an antitumor antibiotic,and is commonly used in the standard treatment for a wide range of cancers.Ho......
Polymeric micelles with tunable channels (PMTC) have been prepared with two kinds of diblock copolyrners and used fo......
目的：合成聚（2-乙基-2-噁唑啉）-聚乳酸（PEOz-PLA）嵌段共聚物,制备包载紫杉醇的PEOzPLA聚合物胶束,并对其理化性质进行评价。方法：采用开......
目的:综述聚合物胶束作为药物载体在经皮传递系统中的应用进展。方法:根据国内外发表的最新文献,对聚合物胶束的制备方法、促进皮......
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口服给药是患者顺应性最好的给药方式,而小肠上皮是口服药物吸收的主要屏障.为了克服小肠上皮屏障口服递送难溶性药物,本研究设计......
Functional Amphiphilic Poly(2-oxazoline)Block Copolymers as Drug Carriers:the Relationship between S
Poly(2-oxazoline)(POx)is a kind of polymeric amides that can be viewed as conformational isomers of polypeptides with ex......
